Status:
UNKNOWN
Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype
Lead Sponsor:
Hospitales Universitarios Virgen del Rocío
Collaborating Sponsors:
Fondo de Investigacion Sanitaria
Conditions:
Obstructive Chronic Pulmonary Disease
Emphysema
Eligibility:
All Genders
45-85 years
Phase:
PHASE4
Brief Summary
AIM: To identify those mechanisms involved in the systemic and muscular response to exercise treatment, in two different Obstructive Chronic Pulmonary Disease (COPD) phenotypes (emphysema and non-emph...
Detailed Description
STUDY POPULATION: Patients diagnosed COPD using the criteria established by the ATS (American Thoracic Society) and the SEPAR (Spanish Society of Pneumology and Thoracic Surgery) obstruction presentin...
Eligibility Criteria
Inclusion
- COPD patients diagnosed according to criteria established by the ATS (American Thoracic Society) and the SEPAR (Spanish Society of Pneumology and Thoracic Surgery) obstruction presenting moderate to severe airway obstruction (FEV1 \<60%) and a clinical impact of their disease. Patients should be stable and appropriate therapy, and must not have suffered exacerbations of the disease over a period of three months before the study, and without treatment with oral corticosteroids for at least the same period.
Exclusion
- Other cardio-respiratory diseases, cardiovascular, neuromuscular or metabolic might interfere with the results.
- Systemic diseases, alcohol intake (\> 80 g / day) or treatment with drugs with potential effect on muscle structure
- Inability or disagree to participate in an exercise program.
Key Trial Info
Start Date :
January 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2012
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01431625
Start Date
January 1 2011
End Date
December 1 2012
Last Update
September 9 2011
Active Locations (1)
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1
Hospital Universitario Virgen del Rocío
Seville, Sevilla, Spain, 41013