Status:

COMPLETED

A Study for Absorption of Intranasal Epinephrine Compared to Conventional Intramuscular Epinephrine

Lead Sponsor:

Siriraj Hospital

Collaborating Sponsors:

Mahidol University

Conditions:

Anaphylaxis

Eligibility:

All Genders

18-30 years

Phase:

NA

Brief Summary

This study is a preliminary report of pharmacokinetic data of epinephrine administered via intranasal route (IN) comparing with intramuscular (IM) route in healthy adult volunteers.

Detailed Description

Patients are reluctant to use Epipen® on emergency basis, perhaps because of improperly training, hesitancy and fear of needle. Other route of administration of epinephrine (EPI) may be more benefit s...

Eligibility Criteria

Inclusion

  • Healthy subjects
  • 18-30 years-old

Exclusion

  • Pregnancy
  • Subjected who use current medication that interfere with result of plasma epinephrine level such as pseudoephedrine

Key Trial Info

Start Date :

July 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2011

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT01432522

Start Date

July 1 2010

End Date

September 1 2011

Last Update

September 13 2011

Active Locations (1)

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Facaulty of Medicine, Siriraj Hospital

Bangkok, Bangkok, Thailand, 10700