Status:
COMPLETED
Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor Progression
Lead Sponsor:
Children's Oncology Group
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Childhood Germ Cell Tumor
Extragonadal Germ Cell Tumor
Eligibility:
All Genders
Brief Summary
RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It ma...
Detailed Description
OBJECTIVES: * Explore inter-tumoral heterogeneity in DNA methylation by tumor histology. * Determine the genomic methylation pattern in the tumors. * Correlate methylation pattern with tumor histolog...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Tumor and blood specimens from patients registered on the Children Oncology Group (COG) Germ Cell Tumor Protocols, and from other study sites for non-COG patients, including Children's Medical Center, Dallas and the Dana-Farber Cancer Institute, Boston
- Patients' clinical data
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- Not specified
Exclusion
Key Trial Info
Start Date :
October 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2016
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT01433224
Start Date
October 1 2011
End Date
May 1 2016
Last Update
May 18 2016
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