Status:
COMPLETED
Comparison of Three Different Prophylactic Treatments of Postoperative Nausea and Vomiting (PONV) in Children
Lead Sponsor:
Centre Hospitalier Universitaire Vaudois
Conditions:
Postoperative Nausea and Vomiting
Eligibility:
All Genders
2-10 years
Phase:
PHASE4
Brief Summary
Incidence of postoperative nausea and vomiting (PONV) in children after tonsillectomy with or without adenoidectomy may be as high as 75%. Several medications may prevent and treat PONV, such as ster...
Detailed Description
Tonsillectomy with or without adenoidectomy may be associated with severe postoperative nausea and vomiting (PONV). Causes are principally trigeminal nerve stimulation and presence of blood in the sto...
Eligibility Criteria
Inclusion
- children aged 2-10 y.
- children ASA 1-2
- weight \> 15 kg
- tonsillectomy with or without adenoidectomy
Exclusion
- intravenous induction
- contraindication to steroids
- contraindication to antidopaminergic drugs
- contraindication to serotoninergic antagonists
- administration of steroids, antidopaminergic drugs, or serotoninergic antagonists in the 24 hours before the surgery
- refusal of parents
- no-french speaking parents
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2013
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT01434017
Start Date
November 1 2008
End Date
June 1 2013
Last Update
February 27 2014
Active Locations (1)
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1
Centre Hospitalier Universitaire Vaudois and University of Lausanne
Lausanne, Canton of Vaud, Switzerland, 1011