Status:
COMPLETED
Diagnostic Accuracy of Cardiac CT Perfusion Compared to PET Imaging
Lead Sponsor:
University of Washington
Conditions:
Myocardial Ischemia
Coronary Artery Disease
Eligibility:
All Genders
20-80 years
Brief Summary
This purpose of this research project is to test the diagnostic accuracy (i.e., sensitivity, specificity, positive and negative predictive value, and receiver operator curve area under the curve) of c...
Detailed Description
Chest pain and other symptoms can occur as a result of blockages in the arteries that supply the heart; these arteries are called the "coronary arteries". Blockages in the coronary arteries may decrea...
Eligibility Criteria
Inclusion
- Patients referred for
- clinically indicated PET imaging for assessment of myocardial ischemia
- clinically indicated CCTA scanning with known coronary artery disease
- ≥20 years of age and ≤ 80 years of age
- Able to provide written informed consent
Exclusion
- Contraindications to beta blockers or regadenoson
- Active reactive airway disease
- 2nd or 3rd degree heart block (without a pacemaker)
- Sick sinus syndrome (without a pacemaker)
- Long QT syndrome (QTC \> 500 msec)
- Severe hypotension
- Decompensated heart failure
- Pregnancy
- Contraindications to undergoing any CT imaging procedure with contrast:
- Irregular heart rhythm despite beta blockade
- Creatinine \>1.6 mg/dl
- Allergy to iodinated contrast medium
- Inability to lie flat
Key Trial Info
Start Date :
September 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2019
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT01434043
Start Date
September 1 2011
End Date
December 31 2019
Last Update
May 9 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Washington Medical Center
Seattle, Washington, United States, 98115