Status:

UNKNOWN

Eye Movement Recording as an Early Differential Diagnostic Tool for Alzheimer/Depression

Lead Sponsor:

Centre Hospitalier Universitaire de Besancon

Collaborating Sponsors:

Laboratoire de psychologie EA 3188

Centre Hospitalier Universitaire Dijon

Conditions:

Alzheimer Disease

Depression

Eligibility:

All Genders

60+ years

Phase:

NA

Brief Summary

The global aim of our study is to validate eye movement recording as an early differential diagnostic tool, in order to discriminate as early as possible between neurodegenerative dementias of Alzheim...

Eligibility Criteria

Inclusion

  • subject whose visual acuity \> 9/10
  • subject without a diagnosis of eye disease
  • subject without a neuropsychological sequelae
  • for depressed patients :subject with a diagnosis of depression confirmed by a psychiatric evaluation and MADRS (Montgomery and Asberg Depression Rating Scale) score \>25 and without cognitive impairment or any other psychiatric pathology and MMSE (Mini Mental State Examination)≥18 and without symptoms of AD
  • for Alzheimer patients :subject with AD diagnosed according to NINCDS-ADRDA (National Institute of Neurological and Communicative Disorders and Stroke -Alzheimer's Disease and Related Disorders Association) criteria and MMSE ≥18 and without psychiatric disorder and MADRS score \< 25
  • for control patients : subject without AD, depression or any other psychiatric condition identified by the diagnostic criteria or cognitive disorders and MADRS score \<25 and MMSE \> 20

Exclusion

  • subject age under 60

Key Trial Info

Start Date :

April 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2018

Estimated Enrollment :

288 Patients enrolled

Trial Details

Trial ID

NCT01434940

Start Date

April 1 2010

End Date

July 1 2018

Last Update

July 31 2017

Active Locations (1)

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1

Univserity Hospital of Besançon - Psychiatry Department

Besançon, France, 25000