Status:

UNKNOWN

Effects of Different Exercise Training Regimens on Visceral Fat Dynamic and Resting Energy Expenditure in Obese Patients

Lead Sponsor:

University of Leipzig

Conditions:

Abdominal Obesity

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

In this project, the investigators will test the hypothesis that predominant (two to three times a week 60 min) strength training is more effective in reducing visceral fat mass than endurance trainin...

Detailed Description

Strength training (ST) was shown to be more effective than endurance training (ET) in improving glycemic control in the treatment of type 2 diabetes. However, it is unknown, whether different training...

Eligibility Criteria

Inclusion

  • BMI \>= 35 kg/m2
  • waist circumference \>102cm (men), \>88cm (women)
  • age 18 - 60 years
  • written informed consent

Exclusion

  • type 1 or type 2 diabetes
  • fasting plasma glucose \>= 6.0 mmol/l
  • 2h-OGTT (oral glucose tolerance test) glucose \>= 11.1 mmol/l
  • any chronic inflammatory or malignant disease
  • medical treatment which influences glucose metabolism
  • drug or alcohol abuse
  • psychiatric disorders
  • untreated thyroid dysfunction
  • cardiac pacemaker or other contraindication for MRI
  • attendant therapy with oral antidiabetic medication, GLP-1 mimetics or analoga, Insulin, anti-obesity medication (orlistat, sibutramine), Falithrom, antipsychotic drugs, any chemotherapeutics
  • pregnant or nursing women
  • expected low compliance
  • current participation in another investigational trial
  • last exercise training \<= 6 months ago

Key Trial Info

Start Date :

April 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2016

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT01435057

Start Date

April 1 2011

End Date

April 1 2016

Last Update

May 28 2015

Active Locations (1)

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1

University of Leipzig, Department of Medicine

Leipzig, Saxony, Germany, 04103