Status:
WITHDRAWN
Hypoalbuminemia in Burn Patients
Lead Sponsor:
Centre hospitalier de l'Université de Montréal (CHUM)
Collaborating Sponsors:
Centre de Recherche du Centre Hospitalier de l'Université de Montréal
Conditions:
Second or Third Degree Burns
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether 5% human albumin solution, given to correct hypoalbuminemia, could improve organ dysfunction in burn patients as assessed by a change in the SOFA scor...
Detailed Description
Each year approximately 2 million people are burned in the USA, from which 80,000 are hospitalized and 6,500 die. It is a well known fact that the two most important factors for mortality in burn pati...
Eligibility Criteria
Inclusion
- Patients admitted to the BICU in the Centre hospitalier de l'Université de Montréal within 24 hours following their thermal burn injury.
- Patients with second or third degree burns greater or equal than 20% of total body surface area.
- Patients aged 18 years or older. -
Exclusion
- Patients with serum albumin greater than 30 g/dl at the time of randomization.
- Patients with a do not resuscitate order.
- Patients needing total parenteral nutrition.
- Patients with the following chronic diseases that could affect baseline SOFA calculation or serum albumin levels: end-stage kidney disease, nephrotic syndrome, hepatitis, exudative enteropaty, chronic thrombocytopenia or hematological malignancy.
- Patients with a known reaction to albumin.
- Pregnant or lactating women.
- Patients younger than 18 years old. -
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2015
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01436292
Start Date
September 1 2011
End Date
October 1 2015
Last Update
November 17 2022
Active Locations (1)
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1
Centre hospitalier de l'Université de Montréal (CHUM)
Montreal, Quebec, Canada, H2W 1T8