Status:
COMPLETED
Oxidative Stress in Hypobaric Hypoxia
Lead Sponsor:
Insel Gruppe AG, University Hospital Bern
Collaborating Sponsors:
Swiss National Science Foundation
Kantonsspital Aarau
Conditions:
Hypobaric Hypoxia
Metabolomics
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The trial investigates changes in metabolism during high altitude expedition up to 6865m. A mass-spectrometry based platform is used to detect different oxidative stress related metabolites. Symptoms ...
Detailed Description
Background Altitude related illness, which include acute mountain sickness (AMS), high altitude pulmonary edema (HAPE) and high altitude cerebral edema (HACE), is common in subjects exposed to high a...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- healthy
- physical fit
- mountaineering experience
- 18-70 years
- Exclusion Criteria
- any type of disease
- regular intake of medicaments
- history of high altitude pulmonary edema
- severe acute mountain sickness below an altitude of 3500m
- any history of high altitude cerebral edema
Exclusion
Key Trial Info
Start Date :
March 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2010
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT01436383
Start Date
March 1 2005
End Date
February 1 2010
Last Update
September 21 2011
Active Locations (1)
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1
Center of Laboratory Medicine
Aarau, Switzerland, 5001