Status:

TERMINATED

Comparison of Diagnostic Performance of an Algorithm and a High Definition Classical Iterative Algorithm Positron Emission Tomography (PET) to 18Fluoro-deoxy-glucose (18FDG) in the Evaluation of Axillary Lymph Node Invasion of Breast Tumors

Lead Sponsor:

Centre Francois Baclesse

Conditions:

Breast Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

The primary endpoint of this study is to show that this algorithm in high definition is superior to the classical algorithm in the diagnosis of lymph node metastases.

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Informed consent and signed by the patient
  • Age ≥ 18 years
  • Breast tumor for which the therapeutic indication for surgery has from the outset: breast surgery (conservative or radical) associated with a conventional axillary dissection
  • Proof of infiltrating ductal carcinoma histology
  • No known metastasis
  • No cons-indication to anesthesia.
  • Exclusion criteria:
  • History of neoadjuvant therapy
  • Patients with invasive lobular carcinoma
  • Indication of the use of sentinel node (if invasive carcinoma uni-centric, ≤ 2 cm in diameter, without palpable lymphadenopathy (N0))
  • Diabetes is not controlled by conventional treatment (blood glucose\> 1.8 g / l)
  • Inability to capital
  • Patients who are pregnant or nursing or of childbearing potential and not using adequate contraception
  • Persons deprived of their liberty
  • Major subject of a measure of legal protection or unable to consent
  • Refusal to participate

Exclusion

    Key Trial Info

    Start Date :

    March 1 2009

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    August 1 2012

    Estimated Enrollment :

    63 Patients enrolled

    Trial Details

    Trial ID

    NCT01436591

    Start Date

    March 1 2009

    End Date

    August 1 2012

    Last Update

    September 10 2012

    Active Locations (1)

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    1

    Centre François Baclesse

    Caen, France, 14076