Status:
UNKNOWN
Weight Reduction Alone May Not be Sufficient to Maintain Disease Remission in Obese Patients With Psoriasis
Lead Sponsor:
Universita di Verona
Conditions:
Psoriasis
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
The relative risk of psoriasis and its severity are directly related to the body mass index (BMI).Patients with psoriasis likely undergo a vicious circle where obesity and skin disease reinforce each ...
Detailed Description
Chronic plaque psoriasis is an inflammatory skin disease associated with obesity in 13-34% of cases. In recent years, the prevalence of overweight and obesity has increased in almost all developed cou...
Eligibility Criteria
Inclusion
- patients ≥ 18 year of age with moderate to severe psoriasis and a BMI ≥ 30 and without psoriasis arthritis, who were treated with methotrexate and had obtained a reduction in psoriasis severity of at least 75% (PASI 75) for the 12 weeks before enrolling into the study.
- all patients gave their written informed consent before any study-related procedures were performed.
Exclusion
- other types of psoriasis (guttate, erythrodermic and pustular psoriasis) and severe obesity (BMI \>35).
- exclusion criteria were other types of psoriasis (guttate, erythrodermic and pustular psoriasis) and severe obesity (BMI \>35).
Key Trial Info
Start Date :
November 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2012
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT01439425
Start Date
November 1 2011
End Date
November 1 2012
Last Update
September 23 2011
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