Status:
COMPLETED
Aprepitant for Postoperative Nausea and Vomiting in Laparoscopic Hysterectomy
Lead Sponsor:
Gachon University Gil Medical Center
Collaborating Sponsors:
Asan Medical Center
University of California, San Francisco
Conditions:
Postoperative Nausea and Vomiting
Eligibility:
FEMALE
21-60 years
Phase:
NA
Brief Summary
* Gynecological surgery is associated with a high incidence of postoperative nausea and vomiting. * NK1 receptor antagonists such as aprepitant appear to be highly effective for treating acute and del...
Detailed Description
123 female patients (ages 21-60) undergoing laparoscopic hysterectomy 1. 80mg aprepitant 2. 125mg aprepitant 3. placebo Incidences of nausea, vomiting/retching, and use of rescue antiemetics were re...
Eligibility Criteria
Inclusion
- female laparoscopic hysterectomy isoflurane anesthesia postoperative opioid use
Exclusion
- liver disease neurologic disease active pulmonary disease cardiac arrhythmia allergies to any perioperative medications
Key Trial Info
Start Date :
March 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2010
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT01440673
Start Date
March 1 2010
End Date
September 1 2010
Last Update
September 26 2011
Active Locations (1)
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1
Gil Medical Center Gachon University
Inchon, South Korea, 405-760