Status:
COMPLETED
Comparison of Licorice Versus Sugar-water Gargle for Prevention of Postoperative Sore Throat and Postextubation Coughing
Lead Sponsor:
The Cleveland Clinic
Conditions:
Sore Throat
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
The investigators propose to test the hypothesis that pre-operative gargling with licorice reduces the incidence of sore throat in rest after intubation with double-lumen endotracheal tubes compared t...
Detailed Description
Patients will be premedicated with up to 7.5 mg p.o. midazolam, per routine. They will be told that the study involves two different solutions for prevention of post-extubation sore throat. Patients ...
Eligibility Criteria
Inclusion
- Thoracic surgery with anticipated use of a double-lumen endotracheal tube;
- Anticipated extubation in the operating room;
- ASA Physical Status 1-3;
- Age 18- 90
Exclusion
- Tracheal pathology, including tracheostomy;
- Surgery within the previous four weeks;
- Upper-respiratory tract infection;
- BMI higher exceeding 40 kg/m2;
- Known or suspected allergy to licorice;
- Use of non-steroidal anti-inflammatory drug medication within 24 hours;
- Chronic opioid use;
- Preoperative pain ≥ 2 on an 11-point Likert scale (0 = no pain; 10 = worst pain);
- Known or suspected difficult airway.
Key Trial Info
Start Date :
October 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2011
Estimated Enrollment :
236 Patients enrolled
Trial Details
Trial ID
NCT01444703
Start Date
October 1 2010
End Date
June 1 2011
Last Update
July 20 2016
Active Locations (1)
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1
Universitätsklinik für Anästhesie, Intensivmedizin und Schmerztherapie an der medizinischen Universität Wien
Vienna, Austria