Status:
COMPLETED
Dexmedetomidine in Patients After Intracranial Surgery
Lead Sponsor:
Capital Medical University
Conditions:
Central Nervous System Diseases
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Dexmedetomidine is a highly selective a2-adrenoreceptor agonist that produces dose-dependent sedation and analgesia without respiratory depression. Dexmedetomidine has been used in critically ill medi...
Detailed Description
The PASTrial is a non-commercial, multi-center, randomized, placebo-controlled, double blinded clinical trial. The study compares dexmedetomidine versus normal saline (placebo) in patients after intra...
Eligibility Criteria
Inclusion
- Adult patients after intracranial surgery with delayed extubation
Exclusion
- emergency operation
- brain stem operation
- preoperative consciousness disorders or epilepsy
- bradycardia, hypotension, acute myocardial infarction, second- or third degree heart block, or need continuous infusions of vasopressor before the start of study drug infusion
- patients enrolled in another trial
Key Trial Info
Start Date :
October 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2013
Estimated Enrollment :
192 Patients enrolled
Trial Details
Trial ID
NCT01445639
Start Date
October 1 2011
End Date
February 1 2013
Last Update
January 28 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Neuro-ICU, Beijing Tiantan Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100050