Status:
TERMINATED
Prevention of Post-operative Pneumonia (POPP)
Lead Sponsor:
Washington University School of Medicine
Conditions:
Post-operative Pneumonia
Lung Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
Postoperative pneumonia is a major complication in patients undergoing thoracic surgery. It leads to considerable morbidity and contributes to perioperative morbidity. There is evidence in literature ...
Eligibility Criteria
Inclusion
- Patients with lung lesions undergoing anatomic resection (lobectomy/segmentectomy/bilobectomy/pulmonary sleeve resection/pneumonectomy)
- Patients with poor lung function (FEV1% \<50% or DLCO\<50% predicted or home oxygen requirement) and lung lesions undergoing non-anatomic lung resection (i.e. wedge resection).
- Patients undergoing esophageal resection.
Exclusion
- Patients with ongoing symptomatic dental infections.
- Patients with recent/ongoing pneumonia (\<15 days from initial surgical patient evaluation).
- Patients who've received a therapeutic course of antibiotics within 15 days prior to thoracic surgery.
- Patients with a preexisting tracheostomy.
- Age\<18
- Patients with an allergy to Peridex/chlorhexidine solution
Key Trial Info
Start Date :
September 22 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 13 2015
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT01446874
Start Date
September 22 2011
End Date
December 13 2015
Last Update
November 8 2018
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110