Status:

COMPLETED

Autopsy Follow-up of Subjects Previously Imaged With Florbetapir F 18 (18F-AV-45) PET in Trial 18F-AV-45-A07

Lead Sponsor:

Avid Radiopharmaceuticals

Conditions:

Alzheimer's Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This study is designed to test the relationship between measurements of brain amyloid using florbetapir F 18 PET imaging and true levels of amyloid plaque density as measured by histopathological asse...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Subjects are enrolled in this study if they:
  • Met entrance criteria and were enrolled and imaged in trial 18F-AV-45-A07 (NCT00857415)
  • Gave informed consent for the 18F-AV-45-A07 (NCT00857415) study procedures and brain donation consistent with the legal requirements of the State in which they are enrolled and the State in which they die
  • Consent to participate in the 18F-AV-45-A16 (NCT01447719) extension protocol, if required by the IRB
  • Reconfirm their consent to a research brain autopsy, if required by the IRB.

Exclusion

    Key Trial Info

    Start Date :

    March 1 2010

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    July 1 2011

    Estimated Enrollment :

    110 Patients enrolled

    Trial Details

    Trial ID

    NCT01447719

    Start Date

    March 1 2010

    End Date

    July 1 2011

    Last Update

    March 21 2025

    Active Locations (22)

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    Page 1 of 6 (22 locations)

    1

    Research Site

    Phoenix, Arizona, United States, 85006

    2

    Research Site

    Sun City, Arizona, United States, 85351

    3

    Research Site

    Little Rock, Arkansas, United States, 72211

    4

    Research Site

    Irvine, California, United States, 92697