Status:
COMPLETED
Metabolomic Embryo Profiles of Obese in Vitro Fertilization (IVF) Patients and Their Relationship With Polycystic Ovary Syndrome (PCO)
Lead Sponsor:
Instituto Valenciano de Infertilidad, IVI VALENCIA
Conditions:
Infertility
Obesity
Eligibility:
All Genders
18-38 years
Brief Summary
The present study aims to elucidate if there is a metabolomic profile alteration in the embryos of obese women in order to understand if the reduced implantation rate observed in these patients is dir...
Eligibility Criteria
Inclusion
- BMI \> 30 kg/m2
- Age \< 38 years old
- Non smokers
- First IVF cycle (groups 2 \& 3, not Control group)
- Normal uterus (seen by ultrasound)
- normal basal hormonal profile(FSH,LH,estradiol,testosterone,androstenedione, insulin, SHBG, glucose, AMH)
- Antral follicle count(\> 5 FA for each ovary)
- Menses every 25-35 days.
Exclusion
- \< 5 or \> 20 oocytes retrieved after stimulation cycle
- estradiol \>3000 pg/ml or progesterone \> 1,5 ng/ml on the hCG day.
- \< 2 evolutive embryos in the culture medium.
Key Trial Info
Start Date :
October 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2014
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT01448863
Start Date
October 1 2011
End Date
October 1 2014
Last Update
March 10 2015
Active Locations (2)
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1
IVI Valencia
Valencia, Valencia, Spain, 46015
2
IVI Valencia
Valencia, Spain, 46015