Status:
COMPLETED
Resveratrol-enriched Grape Extract (Stilvid) in Primary and Secondary Prevention of Cardiovascular Disease
Lead Sponsor:
National Research Council, Spain
Collaborating Sponsors:
Hospital General Universitario Morales Meseguer
Conditions:
Cardiovascular Diseases
Eligibility:
All Genders
18-80 years
Phase:
PHASE2
Brief Summary
Resveratrol can exhibit benefits against cardiovascular diseases (CVDs) although the cardioprotective role of resveratrol as part of the human diet is not yet clear. The aim of this trial is to evalu...
Eligibility Criteria
Inclusion
- FOR PRIMARY PREVENTION:
- Lack of known cardiovascular disease (coronary acute syndrome, stable ischemic cardiopathy, peripheric arteriopathy and cerebrovascular diseases).
- Age between 18 and 80 years.
- The above criteria and diabetes mellitus or at least two of the following risk factors:
- Active smoking (10 cigarettes or more per day).
- Arterial hypertension (\>= 140/90 mmHg).
- Hypercholesterolemia (LDL-cholesterol \>130 mg/dL and/or HDL-cholesterol \< 45 mg/dL in women and 50 mg/dL in men).
- Obesity (BMI \> 30 kg/m2)
- FOR SECONDARY PREVENTION:
- Stable patients who coronary syndrome, cerebrovascular accident or peripheric arteriopathy event occurred at least 6 months or more before the recruitment in the study. In addition:
- Age between 18 and 80 years.
- Ejection fraction of left ventricle \>=45%.
- Functional status I or II according to the New York Heart Association.
- Clinic stability in the recruitment (no symptoms of thoracic pain during the last month).
- Lack of residual lesions without vascularization in those patients with catheterism.
Exclusion
- FOR PRIMARY AND SECONDARY PREVENTION:
- Patients who do not satisfy inclusion criteria and:
- Known allergy to grapes
- Pregnancy or lactation
- Intake of nutraceuticals
Key Trial Info
Start Date :
April 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2011
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT01449110
Start Date
April 1 2009
End Date
March 1 2011
Last Update
November 16 2011
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital Morales Meseguer
Murcia, Spain, 30008