Status:
COMPLETED
Influence of Trimethoprim-Sulfamethoxazole for the Recurrence of Ocular Toxoplasmosis
Lead Sponsor:
University of Campinas, Brazil
Collaborating Sponsors:
Fundação de Amparo à Pesquisa do Estado de São Paulo
Conditions:
Ocular Toxoplasmosis
Eligibility:
All Genders
18-60 years
Phase:
PHASE3
Brief Summary
The investigators study aims to determine the effect of prophylactic therapy with Trimethoprim-sulfamethoxazole on the recurrences of toxoplasma retinochoroiditis gondii. This is a randomized, double-...
Detailed Description
The protozoan Toxoplasma gondii is an obligate intracellular parasite, a common cause of intraocular inflammation in the world. The treatment of toxoplasmosis is the sulfonamide group of drugs, which ...
Eligibility Criteria
Inclusion
- Positive IgG result for toxoplasmosis (IgG)
- Ipsilateral scars of retina compatible with previous episode of toxoplasmosis retinochoroiditis
- Unilateral active lesion of chorioretinitis
Exclusion
- Under 18 years of age
- Immunosuppressed patients
- Use of immunosuppressive treatments
- Concomitant chorioretinitis of other causes
- Pregnancy
- Allergy to Sulfonamides
Key Trial Info
Start Date :
October 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2013
Estimated Enrollment :
141 Patients enrolled
Trial Details
Trial ID
NCT01449877
Start Date
October 1 2011
End Date
November 1 2013
Last Update
July 12 2016
Active Locations (1)
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1
University of Campinas - Ophthalmology Department
Campinas, São Paulo, Brazil, 13083570