Status:
COMPLETED
Maternal-fetal CD4 Microchimerism in HiV Exposed Newborns After Spontaneous Delivery and Cesarean Section
Lead Sponsor:
Johann Wolfgang Goethe University Hospital
Conditions:
Human Immunodeficiency Virus
Eligibility:
All Genders
1-10 years
Brief Summary
The aim of this single centre study is to measure maternal CD4+ t-cells in HiV exposed Newborns after spontaneous birth in comparison to cesarean section. This may have an influence on the risk of ve...
Detailed Description
At birth maternal CD4+ t-cells from umbilical cord blood and placenta blood are measured by microchimerism-analysis. After 6 weeks the maternal CD4+ t-cells are measured in the blood of the babies bl...
Eligibility Criteria
Inclusion
- • HiV exposed Newborns with normal risk of HiV transmission.
Exclusion
- HiV exposed Newborns wiht elevated or high risk of HiV transmission.
- HiV exposed Newborns of mothers not full of age.
- missing informed consent of at least the mother
- Outborns
- Asphyxia
- Major congenital defects
- Chromosomal anomalies
Key Trial Info
Start Date :
August 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2015
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT01450059
Start Date
August 1 2011
End Date
August 1 2015
Last Update
February 22 2016
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Clinic of the Johann Wolfgang-Goethe Univeristy
Frankfurt am Main, Hesse, Germany, 60590