Status:
COMPLETED
The Efficacy of Claritin in Healthy Subjects
Lead Sponsor:
University of Chicago
Conditions:
Healthy
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The primary goal of this study is to examine determinants of the efficacy of Claritin.
Detailed Description
Subjects will be given Claritin 10mg tablet. Subjects will be challenged with histamine via skin prick prior to Claritin administration and at 1 and 2 hours post administration. We will measure and re...
Eligibility Criteria
Inclusion
- Inclusion Criteria.
- 1\. Males and females between 18 and 65 years of age.
- Exclusion Criteria.
- Pregnant or lactating women.
- Upper respiratory infection within 14 days of study start.
- Women of childbearing potential not using specific contraception method(s) (i.e., birth control pills, depo Provera, double barrier) as well as women who are breastfeeding.
- Patients with severe medical condition(s) that in the view of the investigator prohibits participation in the study (heart, lung, kidney, neurological, oncologic or liver disease).
- Use of any other investigational agent in the last 30 days.
- Use of medications that may affect skin testing. Specifically, subjects are excluded if they have used an antihistamine during the 4 days preceding their treatment visit.
Exclusion
Key Trial Info
Start Date :
October 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
340 Patients enrolled
Trial Details
Trial ID
NCT01451996
Start Date
October 1 2011
End Date
December 1 2012
Last Update
March 13 2018
Active Locations (1)
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1
University of Chicago
Chicago, Illinois, United States, 60637