Status:
COMPLETED
Diet Oil Induced Stimulation of GLP-1
Lead Sponsor:
University of Copenhagen
Conditions:
Type 2 Diabetes Mellitus
Eligibility:
All Genders
18-65 years
Phase:
EARLY_PHASE1
Brief Summary
Activation of G protein-coupled receptor GPR119 stimulates glucagon-like peptide-1 (GLP-1)release from the intestinal L-cells. Previously, administration of 2-oleyl-glycerol (2-OG) to humans significa...
Detailed Description
Activation of G protein-coupled receptor GPR119 stimulates glucagon-like peptide-1 (GLP-1)release from the intestinal L-cells. Previously, administration of 2-oleyl-glycerol (2-OG) to humans significa...
Eligibility Criteria
Inclusion
- Patients with type 2 diabetes mellitus according to the WHO criteria
- caucasians
- age above 18 years
- BMI 20-30
Exclusion
- kidney disease
- liver disease
- retinopathy
- anaemia
- use of insulin
- use of GLP-1 analogues
- use of DPP-4 inhibitors
Key Trial Info
Start Date :
March 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2012
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT01453842
Start Date
March 1 2011
End Date
March 1 2012
Last Update
December 2 2014
Active Locations (1)
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1
Department of Clinical Physiology
Glostrup Municipality, Denmark, 2600