Status:

COMPLETED

The Role of Exercise-Periodic-Breathing (EPB) in Impaired Ventilation Regulation Dysfunction in Heart Failure Patients

Lead Sponsor:

Chang Gung Memorial Hospital

Conditions:

Impaired Oxygen Delivery

Ischemic Reperfusion Injury

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Heart failure (HF) is a complex syndrome characterized by myocardial dysfunction and an impaired regulatory function of multiple organ systems which were resulted from impaired cardiac output and cons...

Detailed Description

Patients with heart failure display dyspnea on exertion, lower PCO2 and higher ventilatory response to exercise (V E -V CO 2slope), which demonstrated dysregulation of breathing in this disease catego...

Eligibility Criteria

Inclusion

  • cardiac event with optimal medial treatment within 3 months and have 4 more weeks spared from heart disease attack or major cardiac procedure.

Exclusion

  • unstable angina pectoris
  • uncompensated heart failure
  • myocardial infarction during the past 4 weeks
  • complex ventricular arrhythmias
  • orthopedic or neurological limitations to exercise

Key Trial Info

Start Date :

April 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2013

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT01454128

Start Date

April 1 2011

End Date

March 1 2013

Last Update

May 21 2019

Active Locations (1)

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Dept of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital

Keelung, Taiwan, 204