Status:

COMPLETED

Effects of Food Advanced Glycation Endproducts on Vascular Function in Diabetes

Lead Sponsor:

Profil Institut für Stoffwechselforschung GmbH

Collaborating Sponsors:

Heart and Diabetes Center North-Rhine Westfalia

Icahn School of Medicine at Mount Sinai

Conditions:

Type 2 Diabetes Mellitus

Eligibility:

All Genders

20-70 years

Phase:

NA

Brief Summary

Recent evidence supports detrimental effects of advanced glycation endproducts (AGE) on vascular function (VF). Though, the effect of AGE-modified proteins alone on vascular function remained unknown....

Detailed Description

In a double-blind, controlled, randomized, cross-over manner, 19 subjects with T2DM will receive on 2 different days beverages containing either glycated, heat-treated BLG or non-glycated, heat-treate...

Eligibility Criteria

Inclusion

  • Type 2 diabetes mellitus

Exclusion

  • Other types of diabetes
  • Major cardiovascular complications within 6 months prior to screening
  • Major diabetes complications
  • Failure to give informed consent

Key Trial Info

Start Date :

June 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2010

Estimated Enrollment :

19 Patients enrolled

Trial Details

Trial ID

NCT01456026

Start Date

June 1 2009

End Date

May 1 2010

Last Update

October 20 2011

Active Locations (1)

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Heart and Diabetes Center North-Rhine Westfalia

Bad Oeynhausen, North Rhine-Westphalia, Germany, 32545