Status:

COMPLETED

Impact of CYP2C19*17 on the Pharmacokinetics of Proguanil and Clopidogrel

Lead Sponsor:

University of Southern Denmark

Conditions:

CYP2C19 Genotypes

Eligibility:

All Genders

18-65 years

Phase:

PHASE1

Brief Summary

The aim of this study is to investigate if the genetic variant CYP2C19\*17 affects the pharmacokinetics of proguanil and clopidogrel.

Eligibility Criteria

Inclusion

  • Healthy volunteers
  • Written consent
  • Age 18-65
  • CYP2C19\*1 and or CYP2C19\*17 genotype.

Exclusion

  • Daily medication
  • Alcohol abuse
  • Pregnancy
  • Breastfeeding

Key Trial Info

Start Date :

October 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2013

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT01456546

Start Date

October 1 2011

End Date

July 1 2013

Last Update

July 3 2013

Active Locations (1)

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1

Clinical Pharmacology, University of Southern Denmark

Odense, Fyn, Denmark, DK-5000