Status:

COMPLETED

The Effect of Prolonged Postoperative Antibiotics Administration on Rate of Infection in Patients Undergoing Posterior Spine Surgery Requiring a Hemovac Drain

Lead Sponsor:

The London Spine Centre

Conditions:

Postoperative Infection

Eligibility:

All Genders

16+ years

Phase:

PHASE4

Brief Summary

Post-operative antibiotics for infection prophylaxis are routinely given to most surgical patients, and for orthopaedic surgery patients, the standard of care is treatment for 24 hours following any e...

Eligibility Criteria

Inclusion

  • Age 16 and older
  • Require spine surgery for posterior lumbar decompressions, posterior thoracic decompressions, posterior cervical decompressions, posterior lumbar fusions, posterior thoracic fusions, posterior cervical fusions
  • English speaking and able to understand and provide informed consent

Exclusion

  • Known hypersensitivity to antibiotics
  • Severe renal function impairments
  • Antibiotic therapy for concomitant infection at the time of surgery
  • Spine patients not requiring the insertion of a hemovac drain
  • Pregnant
  • Concomitant steroid therapy
  • Permanent residence more than a 5 hour driving distance away from Hospital

Key Trial Info

Start Date :

October 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2018

Estimated Enrollment :

645 Patients enrolled

Trial Details

Trial ID

NCT01458223

Start Date

October 1 2011

End Date

August 1 2018

Last Update

August 20 2018

Active Locations (1)

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1

Victoria Hospital, London Health Sciences Centre

London, Ontario, Canada, N6A 5W9