Status:

COMPLETED

Effect of Replacement Volume of Haemodiafiltration and AST-120 on Toxins, Oxidative Stress and MicroInflammation

Lead Sponsor:

Tungs' Taichung Metroharbour Hospital

Conditions:

Loss of Solute Clearance

Eligibility:

All Genders

20-80 years

Phase:

PHASE4

Brief Summary

Accumulating evidence suggested that increased oxidative stress (OxSt) as well as inflammation are risk factors for cardiovascular events in hemodialysis patients. The incremental effect of online hae...

Detailed Description

Background High convection volume OL-HDF techniques constitute progress towards renal replacement therapy which is most similar to the native kidney. These techniques offer a higher clearance of urem...

Eligibility Criteria

Inclusion

  • Thrice a week for more then
  • Receiving HDF patients who had been treated for \> 3 months
  • Non-smoking
  • Informed Consent
  • No significant change of medication

Exclusion

  • Malignancy
  • Active infection
  • Congestive heart failure (CHF)
  • History of Gastrointestinal Disease(Active peptic ulcer, severe constipation or severe GI dysmotility)

Key Trial Info

Start Date :

January 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2013

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT01458652

Start Date

January 1 2011

End Date

October 1 2013

Last Update

May 9 2014

Active Locations (1)

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1

PS Lim

Taichung, Taiwan, 435