Status:
COMPLETED
Non Invasive Methods to Guide Volume Optimization
Lead Sponsor:
Lena Nilsson
Conditions:
Postoperative Complications
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Goal directed volume therapy means that bolus doses of 150-250 ml colloid fluid is administered to the patient during contemporary measurement of the patients stroke volume. The fluid status is consid...
Detailed Description
The patients are not allowed to eat after midnight. Routine premedication is given with paracetamol and oxynorm/oxycontin. Thrombosis and antibiotic prophylaxis is given according to surgical departme...
Eligibility Criteria
Inclusion
- Open abdominal surgery under general anaesthesia with a planned operation time of at least 120 minutes
- Age ≥ 18 years
Exclusion
- Anaesthesia risk classification ASA ≥ 4
- Arrhythmia; atrial fibrillation or multiple extra systoles
- Aortic - or mitral insufficiency with hemodynamic influence
- Patients who at the preoperative visit by the responsible anaesthesiologist is planned for a more advanced cardiovascular monitoring. The following monitoring is accepted in the study: invasive blood pressure, 5-lead ECG, central venous pressure and urinary output per hour.
- Patients with a pulmonary or other disease that prevents ventilation using a tidal volume of 7 ml/kg (ideal weight) or a positive end expiratory pressure of 5 -10 cm H2O
- Contra indication against synthetic colloids as severely impaired renal or liver function, hyper natremia or allergy to synthetic colloids
- Laparoscopic surgery
- Liver surgery
- Surgery including thoracotomy
- Contraindications against an oesophageal probe such as severe oesophageal varicose veins
Key Trial Info
Start Date :
November 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2015
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT01458678
Start Date
November 1 2011
End Date
February 1 2015
Last Update
September 17 2015
Active Locations (1)
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1
Anestesi-och operationskliniken
Linköping, Sweden, SE - 581 85