Status:

TERMINATED

This Study is to Determine if Degenerative Spinal Pain and Disorders Cause the Levels of Substance P to Change in a Patients Saliva, Blood and/or Cerebrospinal Fluid.

Lead Sponsor:

Carolina Neurosurgery & Spine Associates

Conditions:

Spinal Disease

Spinal Radiculopathy

Eligibility:

All Genders

18-65 years

Brief Summary

The objective of this pilot study is to determine if degenerative spinal disorders such as acute radiculopathy, myelopathy, stenosis, or disc and facet disease cause detectable alterations in Substanc...

Eligibility Criteria

Inclusion

  • Undergoing spinal surgery for medically refractory spinal radiculopathy,
  • myelopathy or neurogenic claudication based on either history, physical examination or radiologic studies demonstrating neural compression or degenerative disc disease.
  • Undergoing surgery for medically refractory axial spinal pain.

Exclusion

  • Previous spinal procedures or operations,
  • radicular pain,
  • history of fibromyalgia,
  • chronic pain,
  • rheumatoid arthritis,
  • autoimmune disorders,
  • HIV,
  • PTSD,
  • Major Depressive Disorder,
  • migraine headaches or active rhinosinusitis,
  • nicotine intake

Key Trial Info

Start Date :

July 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2014

Estimated Enrollment :

53 Patients enrolled

Trial Details

Trial ID

NCT01458938

Start Date

July 1 2009

End Date

April 1 2014

Last Update

February 1 2017

Active Locations (1)

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Carolina Neurosurgery and Spine Associates, P.A.

Charlotte, North Carolina, United States, 28204