Status:

COMPLETED

A Double-blind, Randomized, Parallel Group, Fase III Comparative Study With Rose Hip Powder Powder and Placebo Given to Patients With Mild to Moderate Osteoarthritis in the Knee or/and Hip

Lead Sponsor:

Hyben Vital ApS

Conditions:

Pain

Activities of Daily Living

Eligibility:

All Genders

40+ years

Phase:

PHASE3

Brief Summary

The trial is an investigator-initiated, double-blind, randomized, placebo-controlled phase III study. After the patient has receiving information about the study and after given written informed cons...

Eligibility Criteria

Inclusion

  • Men and women aged 40 + years
  • Osteoarthritis symptoms with duration of more than 6 months
  • One WOMAC-pain visual analogue scale score (VAS score) there are at least 35 mm at rest
  • Subjective morning joint stiffness
  • Clinical symptoms of arthritis diagnosed by the ACR (American College Rheumatology) criteria

Exclusion

  • Patients who have been treated with rose hip extracts or powder within 3 months before screening.
  • Patients who have been treated with ginger, avocado or soybean extracts or powder within 3 months before screening
  • Patients on steroids, TNFalpha or DMARD prior to trial.
  • Patients receiving irregular medical treatment for osteoarthritis.
  • Patients suffering from other joint diseases other than osteoarthritis.
  • Patients who abuse alcohol
  • Patients with a current psychiatric illness, drug and / or alcohol abuse
  • Patients with known allergy to rose hips
  • Presence of other clinically significant medical conditions
  • Patients scheduled for joint or major surgery during the trial.
  • Patients participating in another clinical trial, or have participated in another clinical trial within 3 months before this study.
  • Patients with known compliance problems or who are uncooperative.
  • Pregnant or lactating women.

Key Trial Info

Start Date :

October 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2012

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT01459939

Start Date

October 1 2011

End Date

May 1 2012

Last Update

June 6 2012

Active Locations (1)

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INCUBA Science Park - Skejby

Aarhus, Denmark, 8200