Status:
COMPLETED
STAGES Trial: Study of Adiposity, Growth and Endocrine Stages
Lead Sponsor:
University of Utah
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Obesity
Eligibility:
All Genders
18-30 years
Brief Summary
The investigators propose to conduct a cross-sectional study of 60 participants who are 18-30 years of age to undergo research PET/CT. The purpose of this study is to investigate the relationships bet...
Detailed Description
We propose to conduct a cross-sectional study of 60 participants who are 18-30 years of age to undergo research PET/CT. The purpose of this study is to investigate the relationships between Brown Adip...
Eligibility Criteria
Inclusion
- Males and females, 18-30 years of age at enrollment, who are obese (BMI greater or equal to 30 kg/m2, weight less than 159 kg) and healthy
- Without medications and endocrine/genetic disorders known to affect weight.
- Participants may have insulin resistance, impaired glucose tolerance, dyslipidemia, or hypertension.
Exclusion
- Anyone who refuses participation.
- A genetic syndrome or other endocrine disorder known to cause obesity (Prader-Willi, Cushing Syndrome, Leptin deficiency, etc.).
- Use of the following medications: psychotropics, sulphonylurea, thiazolidinediones, insulin, glucocorticoids, anti-neoplastic agents, angiotensin receptor blocker, angiotensin-converting enzyme inhibitors.
- Pregnancy or history of pregnancy.
- Active infectious disease
- History of CVD or stroke during the previous 36 months
- Total cholesterol 300 mg/dl, triglycerides 400 mg/dl
- Blood pressure 140/90 mmHg
- Fasting plasma glucose 126 mg/dl.
- Diabetes mellitus, type 1 or 2.
Key Trial Info
Start Date :
June 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2015
Estimated Enrollment :
575 Patients enrolled
Trial Details
Trial ID
NCT01460784
Start Date
June 1 2010
End Date
March 1 2015
Last Update
December 3 2015
Active Locations (1)
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1
University of Utah
Salt Lake City, Utah, United States, 84108