Status:

WITHDRAWN

LPS Flex Porous Femoral Components

Lead Sponsor:

Zimmer Biomet

Conditions:

Osteoarthritis

Rheumatoid Arthritis

Eligibility:

All Genders

18-75 years

Brief Summary

This is a prospective multicenter study of the LPS-Flex Porous Femoral Components when used in primary total knee arthroplasty. The purpose of the study is to obtain short-, mid-, and long-term clinic...

Detailed Description

Survival and outcome data on the NexGen LPS-Flex Porous Femoral Components will be done by an analysis of standard scoring system, radiographs and adverse event records. Survivorship will be evaluated...

Eligibility Criteria

Inclusion

  • Patient 18-75 years of age, inclusive;
  • Patient qualifies for a total knee arthroplasty based on physical exam and medical history including at least one of the following: rheumatoid arthritis, osteoarthritis, traumatic arthritis, polyarthritis, collagen disorders, avascular necrosis of the femoral condyle;
  • Post-Traumatic loss of joint configuration, particularly when there is patellofemoral erosion, dysfunction or prior patellectomy;
  • Moderate valgus, varus, or flexion deformities;
  • Patient has undergone a study related informed consent process;
  • Patient is willing and able to provide written consent;
  • Patient is willing and able to cooperate in the required post-operative therapy;
  • Patient is willing and able to complete scheduled follow-up evaluations.

Exclusion

  • Patient has previous history of infection in the affected joint and/or a local or systemic infection that could affect the prosthetic joint;
  • Insufficient bone stock on femoral or tibial surfaces;
  • Skeletal immaturity;
  • Neuropathic arthropathy;
  • Osteoporosis or any loss of musculature or neuromuscular disease that compromises the affected limb;
  • Stable, painless arthrodesis in a satisfactory functional position;
  • Severe instability secondary to the absence of collateral ligament integrity;
  • Patient has rheumatoid arthritis and an ulcer of the skin or a history of recurrent breakdown of the skin because of their risk of postoperative infection is greater;
  • Patient has a known sensitivity or allergy to one or more of the implanted materials;
  • Patient is pregnant or considered a member of a protected population (e.g., prisoner, mental incompetence, unable to understand what clinical trial participation entails, etc.)

Key Trial Info

Start Date :

May 20 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2012

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT01462240

Start Date

May 20 2008

End Date

March 1 2012

Last Update

August 24 2021

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