Status:

COMPLETED

Effects of Azithromycin on Airway Oxidative Stress Markers in Patients With Bronchiectasis

Lead Sponsor:

Instituto de Investigacion Sanitaria La Fe

Collaborating Sponsors:

Sociedad Valenciana de Neumología

Conditions:

Bronchiectasis

Eligibility:

All Genders

16-80 years

Phase:

NA

Brief Summary

The mechanism by which macrolide antibiotics have immune modifying effects independent from its antibacterial activity has not been well established. In the present work, the investigators will analyz...

Detailed Description

The mechanism by which macrolide antibiotics have immune modifying effects independent from its antibacterial activity has not been well established. In the present work, we will analyze the effect of...

Eligibility Criteria

Inclusion

  • Previous diagnosis of bronchiectasis based on lung HRCT and clinical symptoms
  • Clinically stable in previous four weeks without exacerbations
  • Informed consent

Exclusion

  • Bronchiectasis secondary to Cystic fibrosis, pulmonary surgical processes, immune deficiency, emphysema, allergic bronchopulmonary aspergillosis or diffuse interstitial pulmonary diseases
  • Intolerance to macrolides or severe liver disease.

Key Trial Info

Start Date :

October 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2007

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT01463371

Start Date

October 1 2006

End Date

September 1 2007

Last Update

September 29 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University Hospital La Fe

Valencia, Spain, 46026

Effects of Azithromycin on Airway Oxidative Stress Markers in Patients With Bronchiectasis | DecenTrialz