Status:

WITHDRAWN

Analgesic Effect of Pregabalin in Patients Undergoing Total Abdominal Hysterectomy

Lead Sponsor:

Northwestern University

Conditions:

Pain

Eligibility:

FEMALE

18-64 years

Phase:

NA

Brief Summary

Pregabalin will decrease the total amount of opioid required in patients undergoing total abdominal hysterectomy. In addition, pregabalin will decrease the incidence of opioid-related side effects in ...

Eligibility Criteria

Inclusion

  • ASA Physical Status 1-2
  • Age 18-64
  • BMI 18-35
  • Scheduled for elective total abdominal hysterectomy (with or without bilateral salpingo-oophorectomy)
  • Gender: Female
  • Consent: Obtained

Exclusion

  • Patient refusal
  • Allergy to study medication(s)
  • Preoperative use of gabapentinoids
  • Preoperative use of anticonvulsants
  • Daily use of analgesics
  • Hepatic disease
  • Renal insufficiency (Cr \>2.0)
  • Alcohol or drug abuse
  • Pregnancy
  • Language: Non-English speaking
  • Patient expected to remain intubated after procedure
  • Dropout:
  • Patient request
  • Surgeon request
  • Allergic reaction to pregabalin
  • Surgical procedure significantly altered from scheduled procedure

Key Trial Info

Start Date :

January 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT01466101

Start Date

January 1 2011

Last Update

February 20 2012

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Analgesic Effect of Pregabalin in Patients Undergoing Total Abdominal Hysterectomy | DecenTrialz