Status:
WITHDRAWN
Prospective Study of Clostridium Difficile in Children Undergoing Colonoscopy
Lead Sponsor:
State University of New York at Buffalo
Conditions:
C. Difficile Infection
Eligibility:
All Genders
7-21 years
Phase:
NA
Brief Summary
The investigators found that community acquired C. diff occurs in children undergoing a colonoscopy. When they were treated their symptoms got better. But, the investigators do not know if the treatme...
Detailed Description
Clostridium difficile (CD) is a gram positive, spore forming anaerobic bacillus that is not a normal commensal of the gastrointestinal tract. It was initially named "difficult clostridium" because it ...
Eligibility Criteria
Inclusion
- Aspirate at colonoscopy positive for C. diff.
- Any gender
- Any race
- Age between 7-21
- Greater than 21 kg
- Able to swallow pills
Exclusion
- Abdominal tenderness and distention with minimal diarrhea
- History of inflammatory bowel disease
- Fever
- Systemic toxicity or allergy to metronidazole
- Short bowel syndrome
- History of bowel resection vii
- History of abdominal surgery (excluding appendectomy or cholecystectomy)
- History of hirschsprungs disease x
- Pregnant
- Inability to participate in phone surveys
- Inability to maintain scheduled clinic follow up
- At time of Colonoscopy:
- Visual evidence of pseudomembranes
- Visible ulcerations
- Mucosal friability iv.
- Fissures/fistulas
Key Trial Info
Start Date :
December 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01472978
Start Date
December 1 2011
End Date
December 1 2014
Last Update
July 25 2019
Active Locations (1)
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1
Women and Children's Hospital
Buffalo, New York, United States, 14222