Status:

COMPLETED

Significance of Ficolin 2 in the Determination of Serological Activity in Chronic Inflammatory Bowel Disease

Lead Sponsor:

University of Bern

Collaborating Sponsors:

University Hospital, Basel, Switzerland

University of Lausanne Hospitals

Conditions:

Crohn Disease

Eligibility:

All Genders

18-70 years

Brief Summary

Background Determining disease activity in IBD is sometimes difficult and, to be accurate, requires endoscopy. The serum marker CRP has not proven sufficiently valuable as a marker for IBD specific in...

Detailed Description

Background Background Like mannan-binding lectin (MBL), ficolins are important soluble receptors for microbial associated molecular patterns leading to the activation of the lectin pathway complement...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • known IBD
  • endoscopy for clinical reasons
  • enrolled in the Swiss IBD cohort study
  • Exclusion Criteria

Exclusion

    Key Trial Info

    Start Date :

    October 1 2011

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    June 1 2013

    Estimated Enrollment :

    136 Patients enrolled

    Trial Details

    Trial ID

    NCT01473927

    Start Date

    October 1 2011

    End Date

    June 1 2013

    Last Update

    March 12 2014

    Active Locations (3)

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    Page 1 of 1 (3 locations)

    1

    Gastroenterology and Hepatology, Basel University Hospital

    Basel, Canton of Basel-City, Switzerland, 4031

    2

    DCR, Gastroenterology, Bern, University of Bern

    Bern, Canton of Bern, Switzerland, 3010

    3

    Service de gastro-entérologie et hépatologie, CHUV Lausanne

    Lausanne, Canton of Vaud, Switzerland, 1011