Status:

COMPLETED

Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative Study

Lead Sponsor:

The University Clinic of Pulmonary and Allergic Diseases Golnik

Conditions:

Pleural Effusion

Pleural Diseases

Eligibility:

All Genders

18+ years

Phase:

PHASE2

PHASE3

Brief Summary

The purpose of this study is to compare cryobiopsies with forceps biopsies during semirigid thoracoscopy.

Detailed Description

The investigators are going to compare diagnostic yield and size, morphological features, immunohistochemistry as measures of the quality of the samples. The secondary aim is to evaluate safety with f...

Eligibility Criteria

Inclusion

  • 18 or more years old
  • unilateral pleural effusion of unknown origin
  • pleural irregularities suspicious for pleural malignancy
  • referral for thoracoscopy after less invasive means of diagnosis had failed

Exclusion

  • uncontrolled bleeding tendency
  • unstable cardiovascular status
  • severe heart failure
  • ECOG performance status 4
  • persistent hypoxemia after evacuation of pleural fluid
  • pleural symphisis, fibrothorax

Key Trial Info

Start Date :

November 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2014

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT01475084

Start Date

November 1 2011

End Date

November 1 2014

Last Update

September 10 2015

Active Locations (1)

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University Clinic Golnik

Golnik, Golnik, Slovenia, 4204