Status:
UNKNOWN
Effect of Remote Ischemic Perconditioning on Acute Kidney Injury in Adult Valve Replace
Lead Sponsor:
Central South University
Conditions:
Rheumatic Disease of Heart Valve
Ischemic Reperfusion Injury
Eligibility:
All Genders
20-70 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether Remote Ischemic Perconditioning is effective on Acute kidney injury in adult valve replacement.
Detailed Description
Methods: Patients meeting the requirement will be randomized into 2 groups: the treatment group consisted of three 5-minute cycles left lower limb ischemia, induced by inflating a blood pressure cuff ...
Eligibility Criteria
Inclusion
- rheumatic heart valve disease requiring selective aortic or double valve(aortic and mitral valve) replacement
Exclusion
- infective endocarditis congenital valve disease previous cardiac surgery complicated with rereplace valve
- Renal dysfunction
- diabetes
- coronary artery disease
- hypertension
- peripheral vascular disease affecting the lower limb free of arteriovenous fistula
- receiving aspirin, corticosteroids, angiotensin-converting enzyme inhibitors or statin perioperatively
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2012
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT01476969
Start Date
September 1 2011
End Date
November 1 2012
Last Update
August 14 2012
Active Locations (1)
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1
Central South University
Changsha, Hunan, China, 410008