Status:

COMPLETED

Multimodal Assessment of Neurobiological Markers for Psychiatric Disorders

Lead Sponsor:

Medical University of Vienna

Conditions:

Major Depressive Disorder (MDD)

Anxiety Disorder

Eligibility:

All Genders

18-50 years

Phase:

PHASE4

Brief Summary

MAN-BIOPSY pursues the concrete research question whether novel biological and psycho-physiological clusters or categories can be defined to improve treatment and minimize side effects in psychiatry, ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for patients:
  • DSM-IV-TR diagnosis of MDD or an anxiety disorder (excluding PTSD, specific phobias, and bipolar disorder) by a structured clinical interview (SCID)
  • aged 18 to 50 years
  • drug-free within the last three months prior inclusion
  • willingness and competence to sign the informed consent form
  • Inclusion Criteria for remitted subjects:
  • a previous DSM-IV-TR diagnosis of MDD or an anxiety disorder (excluding PTSD, specific phobias, and bipolar disorder) but no symptoms at present, determined by SCID
  • aged 18-50 years
  • drug-free within the last three months prior inclusion
  • willingness and competence to sign the informed consent form
  • Inclusion Criteria for healthy control subjects:
  • Inclusion criteria for healthy control subjects are
  • willingness and competence to sign the informed consent form
  • aged 18-50 years
  • drug-free
  • Exclusion Criteria:
  • concomitant major internal or neurological illness
  • concomitant psychiatric disorders (except depression and anxiety for patients, excluding PTSD, claustrophobia and bipolar disorder)
  • ingestion of any antipsychotic, antidepressant, or anti-anxiety agent within the last three months prior to the screening visit
  • current substance abuse
  • failure to comply with the study protocol or to follow the instructions of the investigating team

Exclusion

    Key Trial Info

    Start Date :

    November 1 2011

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    September 1 2016

    Estimated Enrollment :

    289 Patients enrolled

    Trial Details

    Trial ID

    NCT01477203

    Start Date

    November 1 2011

    End Date

    September 1 2016

    Last Update

    September 14 2016

    Active Locations (1)

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    1

    Medical University of Vienna, Department for Psychiatrie and Psychotherapie

    Vienna, Vienna, Austria, 1090