Status:

COMPLETED

Bioavailability of Three Oral Formulations for Hormone Replacement Therapy in Postmenopausal Women

Lead Sponsor:

Novo Nordisk A/S

Conditions:

Menopause

Healthy

Eligibility:

FEMALE

50-70 years

Phase:

PHASE1

Brief Summary

This trial is conducted in Europe. The aim of this trial is to determine the extent of bioavailability of two low dose estradiol/norethisterone acetate (NETA) preparations with a marketed estradiol/no...

Eligibility Criteria

Inclusion

  • Healthy
  • Postmenopausal
  • Caucasian race
  • Smoking (up to 5 cig./per day) is allowed
  • Good state of health: evidenced by medical history, physical examination including gynecological examination, results of laboratory examination

Exclusion

  • Known or suspected allergy to trial products or related products
  • Previous participation in this trial
  • Previous estrogen and/or progestin hormone replacement therapy
  • Known, suspected or history of breast cancer
  • Systolic blood pressure (BP) at least 160 mm Hg and/or diastolic BP at least 100 mm Hg, currently treated or untreated
  • Body Mass Index (BMI) above 35.0 kg/m\^2

Key Trial Info

Start Date :

March 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2005

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT01477632

Start Date

March 1 2005

End Date

June 1 2005

Last Update

January 15 2016

Active Locations (1)

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1

Neu-Ulm, Germany, 89231