Status:
TERMINATED
Effects of Omega-3 Fatty Acid Supplementation on Inflammatory Response in Multisystem Trauma Patients
Lead Sponsor:
University of Cincinnati
Conditions:
Multiple Trauma
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
PHASE2
Brief Summary
This study will evaluate the effects of omega-3 fatty acid supplementation on inflammation in trauma patients. The main hypothesis is that such supplementation will reduce the presence of biomarkers o...
Detailed Description
This prospective, randomized study will evaluate the effects of omega-3 fatty acid supplementation on inflammatory response in multi-injured trauma patients. Its primary objective is to compare the in...
Eligibility Criteria
Inclusion
- Multi-system blunt trauma patients
- Ages 18 through 65 years, inclusive
- Admission to ICU
- Nasogastric or nasoenteric feeding tube in place
- Intention of primary medical team to feed the patient enterally
Exclusion
- Expected mortality within 48 hours
- Intracranial hemorrhage
- Pregnant or breast feeding
- Patient, surrogate, or physician not committed to full support
- Refractory shock
- Unable to obtain enteral access
- Presence of partial or complete mechanical bowel obstruction, or ischemia, or infarction
- Current total parenteral nutrition (TPN) use, or intent to use TPN within 7 days
- Current gastrointestinal bleeding
- Requirement for vasopressors
Key Trial Info
Start Date :
June 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2012
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT01477697
Start Date
June 1 2011
End Date
November 1 2012
Last Update
February 25 2013
Active Locations (1)
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1
University Hospital
Cincinnati, Ohio, United States, 45219