Status:
COMPLETED
Cortisol Suppression and Startle Responses in Posttraumatic Stress Disorder (PTSD)
Lead Sponsor:
Emory University
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Post Traumatic Stress Disorder
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Posttraumatic stress disorder (PTSD) occurs in some people after exposure to events that cause extreme fear or helplessness. The incidence of war zones worldwide and the prevalence of violence in larg...
Detailed Description
The proposed study will provide innovative tools to tease apart the relationship between amygdala-dependent neurophysiology and HPA-axis sensitivity in a human clinical population. Investigators have ...
Eligibility Criteria
Inclusion
- Able to give informed consent
- Willing to participate in initial assessment and 2 full days of interviews and imaging visit
- Able to understand English and no obvious deficit in comprehension or following directions
- 18-65 years old
Exclusion
- Mental Retardation (per clinical judgment of study physician)
- Psychotic Disorder (per clinical judgment of study physician)
- Acute suicidal ideation
- Pregnancy
- Positive urine drug screen
- Active medical disorders contributing to psychiatric sx e.g. hypo or hyperthyroidism, SLE, advanced cirrhosis, etc. (per clinical judgment of study physician)
Key Trial Info
Start Date :
November 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2015
Estimated Enrollment :
165 Patients enrolled
Trial Details
Trial ID
NCT01477762
Start Date
November 1 2011
End Date
July 1 2015
Last Update
April 18 2017
Active Locations (1)
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1
Grady Health System
Atlanta, Georgia, United States, 30303