Status:
UNKNOWN
Role of Polymorphisms in the Dectin-1 Gene in Determining the Risk of Candida Colonization and Infection in Critically Ill Patients
Lead Sponsor:
Cardiff and Vale University Health Board
Collaborating Sponsors:
Cardiff University
Conditions:
Critically Ill
Eligibility:
All Genders
18+ years
Brief Summary
The principal aim of this study is to establish if a polymorphism in a gene important for innate immunity to fungi represents a significant risk factor for the development of Candida colonisation and ...
Detailed Description
Invasive fungal infections are associated with increased morbidity and mortality rates as high as 50% (1). Up to half occur in non-neutropenic; critically ill patients and the majority are due to Cand...
Eligibility Criteria
Inclusion
- Patients aged \> 18 years
- Patients with anticipated or actual critical care unit stay \> 72 hours
- Consent or assent (if patient lacks capacity) obtained
Exclusion
- Age \< 18 years
- Length of predicted stay on critical care \< 72 hours consent or assent not obtained
Key Trial Info
Start Date :
December 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT01482988
Start Date
December 1 2011
Last Update
December 1 2011
Active Locations (1)
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1
Critical Care Unit
University Hospital of Wales, Cardiff, United Kingdom, CF14 4XW