Status:
COMPLETED
Feasibility Study on Stem Cells Sensitivity Assay
Lead Sponsor:
Associazione Oncologia Traslazionale
Conditions:
Lung Cancer
Colorectal Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Lung Cancer (LC), colorectal cancer (CRC) and breast cancer (BC) are the major killers in oncology, accounting for about 40% of cancer deaths. Although progresses have been made in the last few years,...
Detailed Description
Patients Patients with LC, CRC and BC with good performance status and with tumor tissue available, at failure of conventional therapies or without possibility to be treated with therapy of proven eff...
Eligibility Criteria
Inclusion
- Histologically/cytologically confirmed diagnosis of metastatic LC, CRC or BC
- Availability of tumor tissue suitable for CSCs extraction
- Performance status of 100% according to Karnofsky score
- Failure of conventional therapies or no therapy of proven efficacy
- Adequate hematological, renal and liver functions
- No concomitant comorbidity potentially interfering with the study
- Informed consent form signature.
Exclusion
- Performance status \<100% according to Karnofsky score
- Patient suitable for standard therapies
- Important comorbidity interfering with the study
- Significant alteration of liver, hematological or renal function(s)
- No informed consent form signature
Key Trial Info
Start Date :
November 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT01483001
Start Date
November 1 2011
End Date
December 1 2013
Last Update
January 14 2015
Active Locations (1)
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1
Department of Medical Oncology
Livorno, Livorno, Italy, 57100