Status:
COMPLETED
Assessment of Efficacy of Low Intensity Resistance Training in Men at Risk for Symptomatic Knee Osteoarthritis
Lead Sponsor:
University of Iowa
Conditions:
Knee Osteoarthritis
Eligibility:
MALE
45+ years
Phase:
NA
Brief Summary
The purpose of this research study is to determine whether low intensity resistance training with concurrent application of a peripheral blood flow restriction device to the exercising limb will elici...
Detailed Description
Over 9.3 million adults over the age of 60 are afflicted with symptomatic knee osteoarthritis (OA) characterized by radiographic findings and consistent knee pain or stiffness. Furthermore, our resear...
Eligibility Criteria
Inclusion
- male
- ≥ 45 years
- has at least one of the following: BMI≥25, frequent knee symptoms on most of the last 30 days, history of knee injury which rendered individual unable to walk without assistance for at least 2 days, history of knee surgery, diagnosis of knee osteoarthritis
Exclusion
- Resistance training at any time in the last 3 months prior to study
- Bilateral knee replacement
- Lower limb amputation
- Lower limb surgery in the last 6 months that affects walking ability or ability to exercise
- Back, hip or knee problems that affect walking ability or ability to exercise
- Unable to walk without a cane or walker
- Inflammatory joint or muscle disease such as rheumatoid or psoriatic arthritis or polymyalgia rheumatica
- Multiple sclerosis
- Known neuropathy
- Self-report of Diabetes
- Currently being treated for cancer or having untreated cancer
- Terminal illness (cannot be cured or adequately treated and there is a reasonable expectation of death in the near future)
- Peripheral Vascular Disease
- History of myocardial infarction or stroke in the last year
- History of deep venous thrombosis
- Chest pain during exercise or at rest
- Use of supplemental oxygen
- Inability to follow protocol (e.g. lack of ability to attend visits or understand instructions)
- Staff concern for subject health (such as history of dizziness/faintness or current restrictions on activity)
- Concurrent study participation
- Unable to attend more than 2 days within any 1 week or unable to attend 4 or more sessions during the study
Key Trial Info
Start Date :
November 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2012
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT01487525
Start Date
November 1 2011
End Date
February 1 2012
Last Update
February 4 2016
Active Locations (1)
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1
University of Iowa
Iowa City, Iowa, United States, 52242