Status:

UNKNOWN

Restrictive Versus Liberal Red Cell Transfusion Strategy in Orthopedic-Oncology Patients Undergoing Surgery - a Randomized Controlled Study

Lead Sponsor:

Tel-Aviv Sourasky Medical Center

Conditions:

Red Blood Cells Transfusion.

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The rationale for perioperative red blood cell (RBC) transfusion is based on the observation that anemia is an independent risk factor for morbidity and mortality after cardiac operations. However, tr...

Eligibility Criteria

Inclusion

  • Consecutive ASA I-III patients, with preoperative hemoglobin 12 gr% or less scheduled for major orthopedic-oncology surgery (one that is expected to carry moderate to severe blood loss) at Tel Aviv Sourasky Medical Center will be included in the study.

Exclusion

  • Patients will be excluded for any of the following reasons:
  • an age of less than 18 years;
  • inability to receive blood products;
  • pregnancy;
  • emergency procedures;
  • hepatic dysfunction (total bilirubin value higher than 1.5 mg/d);
  • end-stage renal disease (receiving chronic dialysis therapy);
  • acute coronary syndrome, active heart or lung disease and refusal to consent.

Key Trial Info

Start Date :

January 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT01491308

Start Date

January 1 2012

Last Update

December 13 2011

Active Locations (1)

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Tel-Aviv Sourasky Medical Center

Tel Aviv, Israel, 64239