Status:
COMPLETED
Integrated Diagnostics Characterization of Right Ventricular Diastolic Flow Dynamics in Pulmonary Arterial Hypertension
Lead Sponsor:
National Jewish Health
Collaborating Sponsors:
Siemens Medical Solutions
Conditions:
Pulmonary Hypertension
Eligibility:
All Genders
18-75 years
Brief Summary
Pulmonary hypertension (PH) is a condition in which high blood pressure develops in the lungs and right side of the heart. People with PH suffer from shortness of breath, chest pain, heart failure, he...
Detailed Description
The adaptive changes that result from chronic pressure overload in pulmonary arterial hypertension (PAH) lead to myocardial hypertrophy, stiffening, and right ventricular diastolic dysfunction (RVDD)....
Eligibility Criteria
Inclusion
- previous diagnosis of PH by right heart catheterization
- RV diastolic dysfunction by echo
- normal RV systolic function
- age 18-75 years old
- no contraindication to MRI
Exclusion
- absence of PH
- absence of RV diastolic dysfunction by echo
- RV systolic dysfunction
- age \< 18 years
- contraindication to MRI
- pregnancy
Key Trial Info
Start Date :
November 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2013
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT01491646
Start Date
November 1 2010
End Date
October 1 2013
Last Update
October 22 2020
Active Locations (1)
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1
National Jewish Health
Denver, Colorado, United States, 80206