Status:

WITHDRAWN

Acupuncture Point Stimulation for Treatment of Chemotherapy Nausea and Vomiting

Lead Sponsor:

Stanford University

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Childhood Acute Lymphoblastic Leukemia

Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies

Eligibility:

All Genders

8-21 years

Phase:

NA

Brief Summary

This randomized pilot clinical trial studies giving acupuncture in reducing nausea and vomiting in patients undergoing chemotherapy. Pressing and stimulating nerves at an acupuncture point on the insi...

Detailed Description

PRIMARY OBJECTIVE: I. To determine whether transcutaneous acupuncture point stimulation (TAPS) at P6 as an adjuvant treatment to standard antiemetic therapy reduces acute chemotherapy induced nausea ...

Eligibility Criteria

Inclusion

  • Patient with a planned admission for at least 24 hours for highly emetogenic or moderately emetogenic chemotherapy at Lucile Packard Children's Hospital or Packard El Camino.
  • Planned to undergo at least 2 more cycles of chemotherapy.
  • Can include but not limited to: children with high risk ALL, AML, Ewing's Sarcoma, Osteosarcoma
  • History of vomiting with prior cycles of chemotherapy (2 episodes of emesis at minimum) despite use of conventional antiemetic medications.
  • Age 8-21.
  • Parent must be able to understand and willing to sign written informed consent document.

Exclusion

  • Prior knowledge of acupuncture or experience with acupuncture or acupressure.
  • There will be no restrictions regarding use of other Investigational Agents.
  • Comorbid Diseases:
  • Diagnosis of any cardiac condition (cardiomyopathy, arrhythmia, pacemaker placement).
  • Any diagnosis requiring pediatric intensive care unit admission.
  • Patients with brain tumor, brain metastasis (these patients often require radiation and surgery in addition to chemotherapy which may confound the results)
  • Concomitant radiation therapy during current chemotherapy cycle.
  • Developmental delay patients with allergy to tape or leads will be excluded from the study.
  • Pregnant patients will be excluded from the study.
  • Cancer survivors will not be excluded from the study as long as they are undergoing chemotherapy treatment for their current cancer therapy.
  • HIV-positive patients will not be excluded.

Key Trial Info

Start Date :

May 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT01492569

Start Date

May 1 2012

Last Update

June 12 2013

Active Locations (1)

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1

Stanford University

Stanford, California, United States, 94305