Status:

COMPLETED

Screening of Children in Household Contact With Adult TB Patients in Mbarara Hospital, Uganda

Lead Sponsor:

Epicentre

Collaborating Sponsors:

Mbarara University of Science and Technology

Medecins Sans Frontieres, Netherlands

Conditions:

Tuberculosis

Eligibility:

All Genders

1-5 years

Brief Summary

The proposed study aims to establish a pilot program through a prospective cohort study offering routine contact tracing, investigation and prophylaxis for LTBI, and treatment of TB disease to childre...

Detailed Description

Because children with tuberculosis (TB) are usually smear-negative and therefore less infectious, they are generally not considered a public health risk. Up to 70% of children living in the same house...

Eligibility Criteria

Inclusion

  • Any child who has lived in the same household with the index case continuously for at least 2 weeks within the 3-month period immediately preceding the diagnosis of smear- positive or culture-positive TB in the index case.
  • Informed consent signed by the parent or legal guardian
  • Living within a 2-hour radius of Mbarara town

Exclusion

  • Child currently receiving anti-tuberculosis treatment
  • Child has received a full course of anti-TB treatment within the last 6 months

Key Trial Info

Start Date :

April 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2014

Estimated Enrollment :

281 Patients enrolled

Trial Details

Trial ID

NCT01492595

Start Date

April 1 2012

End Date

April 1 2014

Last Update

March 2 2016

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