Status:
COMPLETED
Systemic Effects of Chronic Metal Ion Exposure From Metal-on Metal Hip Resurfacing
Lead Sponsor:
Sheffield Teaching Hospitals NHS Foundation Trust
Collaborating Sponsors:
University of Sheffield
Conditions:
Osteoarthritis
Eligibility:
All Genders
18+ years
Brief Summary
In recent years hip resurfacing has become a very popular alternative treatment to total hip replacement for the treatment of hip arthritis. This procedure has become particularly common in the young ...
Detailed Description
This is a cross sectional survey in patients who have had hip resurfacing (MOMHR) and subjects who have received a conventional hip replacement (THA) using a metal on plastic or ceramic bearing. Parti...
Eligibility Criteria
Inclusion
- MOMHR subjects - 35 Men and women at a minimum of 5 years following unilateral or bilateral MOMHR for primary or secondary OA
- Conventional THA subjects - These subjects will be individually (casebycase) matched with MOMHR subjects for age (±3 years), sex, and year of primary arthroplasty surgery (±2 years).
Exclusion
- Known inflammatory arthropathy or metabolic bone disease.
- Use of pharmacological doses of estrogen, progestin, androgen, calcitonin, glucocorticoids, or dietary supplements of calcium or vitamin D within the previous 12 months
- Any previous use of bisphosphonate or fluoride therapy (excluding dental prophylaxis)
- Pregnancy
- Subjects who cannot undergo an MRI scan for medical reasons e.g. those with a cardiac pacemaker
Key Trial Info
Start Date :
November 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2012
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT01493141
Start Date
November 1 2009
End Date
April 1 2012
Last Update
December 17 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, South Yorkshire, United Kingdom, S5 7AU